Premarin: side effects, dosage, special precautions, and more

Premarin is a hormone therapy drug used to treat menopausal symptoms and other conditions. It is a brand name for a combination of conjugated estrogens that are derived from the urine of pregnant mares. Premarin is used to treat symptoms of menopause such as hot flashes, vaginal dryness, and burning sensations. It may also be used to prevent osteoporosis in postmenopausal women, as well as to treat certain prostate and breast cancer conditions.

Premarin was first developed in 1942 by a team at the Wyeth-Ayerst Laboratories. The drug was approved by the FDA in 1942 and has been used to treat menopausal symptoms ever since. The active ingredients in Premarin are conjugated estrogens, which are a combination of estrone, equilin, and equilenin. These estrogens are derived from the urine of pregnant mares.

Premarin is available in multiple forms, including tablets, creams, and vaginal rings. It is typically taken orally, either once a day or several times a day, depending on the condition being treated. Premarin is also available in generic forms, such as conjugated estrogens and estradiol.

Premarin is generally well tolerated, but it can cause side effects such as nausea, vomiting, bloating, breast tenderness, and headaches. It may also increase the risk of stroke, heart attack, blood clots, and breast cancer. Some women may experience an increased risk of developing endometrial cancer if they take Premarin without progestin.

Premarin is a powerful hormone therapy drug that can be used to treat a variety of conditions. It is important to speak with a healthcare provider before using Premarin to ensure it is the right treatment option for you.


Hormone Therapy. (2020). Retrieved from

Premarin (Conjugated Estrogens). (2020). Retrieved from

Premarin (Conjugated Estrogens). (2020). Retrieved from

Leave a Comment

Your email address will not be published. Required fields are marked *