Differin is a topical medication used to treat acne. It is the first retinoid approved by the FDA for over-the-counter use and is available in both gel and cream forms. Differin works by unclogging pores, decreasing oil production, and preventing the formation of new acne.

Differin is primarily used for treating mild to moderate acne, including whiteheads, blackheads, and inflamed pimples. It can also be used to treat acne scars and to reduce the appearance of wrinkles and fine lines.

Differin is applied once daily in the evening, after washing and drying the skin. It is important to use a mild cleanser and to avoid scrubbing the skin too vigorously. It can take up to 12 weeks to see the full effects of Differin, so it is important to use it consistently and as directed.

Common side effects of Differin include skin irritation, redness, dryness, and peeling. It is important to use a gentle moisturizer and sunscreen to help minimize these side effects. If any of these side effects become severe or persist, it is important to contact your doctor.

The active ingredient in Differin is adapalene, which belongs to a class of drugs known as retinoids. Retinoids help to unclog pores, reduce inflammation, and increase cell turnover. Adapalene is also available as a generic drug and is known by the following names: Adaferin, Differine, Adapalen, and Adapalène.

It is important to remember that Differin is not a cure for acne, but rather a treatment that can help to reduce the severity of acne. It is important to use the medication as directed and to be patient, as it can take up to 12 weeks to see the full effects. It is also important to use a gentle moisturizer and sunscreen to help minimize side effects.

If you have any questions or concerns about using Differin, it is important to speak to your doctor or pharmacist. They can provide more information about the medication and help you to decide if it is the right treatment for you.


American Academy of Dermatology. (2020). Treating acne with Differin Gel. Retrieved from: https://www.aad.org/public/diseases/acne-and-rosacea/treating-acne/differin-gel

FDA. (2016). Differin Gel 0.1% (adapalene). Retrieved from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021752s023lbl.pdf

WebMD. (2020). Differin topical. Retrieved from: https://www.webmd.com/drugs/2/drug-7206/differin-top/details

Leave a Comment

Your email address will not be published. Required fields are marked *