Reglan was first approved by the U.S. Food and Drug Administration (FDA) in 1980. It has since been used to treat a variety of gastrointestinal issues, including gastroparesis, which is a condition in which the stomach does not empty properly. Reglan is also used to prevent nausea and vomiting caused by chemotherapy and radiation therapy.
The active ingredient in Reglan is metoclopramide, which is a dopamine antagonist. It works by blocking the action of dopamine, a neurotransmitter that can cause nausea and vomiting. In addition to metoclopramide, Reglan also contains inactive ingredients such as lactose, magnesium stearate, and titanium dioxide.
Reglan is available in tablet and liquid form and is taken orally. The recommended dosage is 10 mg taken three times a day, 30 minutes before meals. It is important to follow the instructions on the label carefully and not to take more than the recommended dose.
Reglan is also available under several brand names, including Metozolv, Maxolon, and Maxeran. It is important to note that the generic version of Reglan may not be as effective as the brand-name versions.
Reglan is generally well-tolerated, but there are some potential side effects, including drowsiness, headache, and constipation. It is important to talk to your doctor if you experience any of these side effects.
In conclusion, Reglan is a medication used to treat gastrointestinal issues, such as nausea, vomiting, heartburn, and gastroparesis. It is also used to prevent nausea and vomiting caused by chemotherapy and radiation therapy. The active ingredient in Reglan is metoclopramide, and it is available in tablet and liquid form. Reglan is generally well-tolerated, but there are some potential side effects. It is important to talk to your doctor if you experience any of these side effects.
References:
1. U.S. Food and Drug Administration (FDA). (2020). Metoclopramide tablets and solution. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/019249s081lbl.pdf
2. Mayo Clinic. (2020). Metoclopramide. Retrieved from https://www.mayoclinic.org/drugs-supplements/metoclopramide-oral-route/description/drg-20073945
3. National Center for Biotechnology Information (NCBI). (2020). Metoclopramide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Metoclopramide