Doxazosin is a medication used to treat hypertension (high blood pressure) and other cardiovascular conditions. It belongs to a class of drugs called alpha-blockers that work by relaxing the muscles of the blood vessels, allowing them to expand and reduce blood pressure. Doxazosin was approved by the U.S. Food and Drug Administration (FDA) in 1994 and is available in both generic and brand name forms.
History of Discovery
Doxazosin was first developed in the late 1980s by the pharmaceutical company Pfizer. It was initially tested as a treatment for benign prostatic hyperplasia (BPH), a condition that affects the prostate in men. However, it was found to be more effective in treating hypertension. After clinical trials, it was approved for use in the United States in 1994.
Active Ingredients and Synonyms
The active ingredient in Doxazosin is doxazosin mesylate. It is available in both generic and brand name forms, including Cardura and Carduran. Other synonyms include doxazosin mesilate, doxazosin mesilate monohydrate, and doxazosin mesylate monohydrate.
Advantages
Doxazosin has several advantages as a treatment for hypertension. It is generally well-tolerated, with few side effects. It is also relatively inexpensive, making it an affordable treatment option. Additionally, Doxazosin does not interact with other medications, so it can be taken with other medications for hypertension.
In summary, Doxazosin is a medication used to treat hypertension and other cardiovascular conditions. It belongs to a class of drugs called alpha-blockers and works by relaxing the muscles of the blood vessels. Doxazosin was first developed in the late 1980s and approved for use in the United States in 1994. The active ingredient in Doxazosin is doxazosin mesylate, and it is available in both generic and brand name forms. Doxazosin has several advantages, including being well-tolerated, inexpensive, and not interacting with other medications.